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compound intra-day variation (%rsd) inter-day variation (%)

1st day 2nd day 3rd day 4th day 5th day 6th day days
1-3 days
4-6 6 day
total

alprazolam 5.04 4.94 5.06 5.38 4.55 4.83 3.19 1.63 2.74

alprazolam-d5 (istd) 5.04 4.68 5.48 5.31 4.26 4.91 2.62 1.89 2.18

area ratio
(alprazolam / alprazolam-d5)
3.48 3.11 3.48 3.44 3.71 3.54 1.79 0.26 1.40

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compound	intra-day variation (%rsd)						inter-day variation (%)
compound	1st day	2nd day	3rd day	4th day	5th day	6th day	days 1-3	days 4-6	6 day total
alprazolam	5.04	4.94	5.06	5.38	4.55	4.83	3.19	1.63	2.74
alprazolam-d5 (istd)	5.04	4.68	5.48	5.31	4.26	4.91	2.62	1.89	2.18
area ratio (alprazolam / alprazolam-d5)	3.48	3.11	3.48	3.44	3.71	3.54	1.79	0.26	1.40